In today’s world, where challenges like climate change, dwindling natural resources, and growing social inequality are reshaping our global landscape, science education at the university level stands at a powerful crossroads. This paper explores how universities can harness science education to drive sustainable development and spark meaningful innovation. It looks at how curricula can be reimagined to reflect the United Nations Sustainable Development Goals (SDGs), emphasizing interdisciplinary learning, hands-on experiences, and real-world problem-solving. Through case studies and policy insights, the study shows how higher education institutions can become hubs of sustainable thinking and practice—places where new technologies, forward-looking mindsets, and practical solutions are born. It also underscores the role of inclusive education, research-informed teaching, and strong partnerships across sectors in equipping students with the tools and values needed for a more sustainable future. By embedding sustainability into both what they teach and how they operate, universities can help shape not only capable graduates, but also a more resilient and innovative society.