The mental health landscape among Indian youth has reached critical proportions, with approximately 20-25% experiencing mental health challenges including depression, anxiety, and existential distress. This research paper examines the role of indigenous Indian philosophical concepts—specifically karma (action and consequence) and dharma (duty and ethics)—in fostering existential resilience among young people in India. Drawing on ancient texts including the Vedas, Upanishads, and Bhagavad Gita, this paper explores how these indigenous coping mechanisms provide culturally resonant frameworks for managing psychological distress and building resilience. The review synthesizes empirical research demonstrating that belief in karma serves as a psychological buffer against stress, promotes emotional regulation, and facilitates meaning-making during adversity. Similarly, adherence to dharma provides moral clarity and purpose, essential components of existential resilience. Findings suggest that these indigenous concepts, when integrated with contemporary mental health practices, offer holistic approaches to addressing the existential and psychological challenges faced by Indian youth. The paper concludes with recommendations for culturally sensitive mental health interventions that honor traditional Indian knowledge systems while meeting the urgent mental health needs of India's young population.