The global market and its drive for competition for the creation and operation of technology transfer offices that established for me between India and industry. It fills an important role of carefully filtering through ideas that can be ass produced for commercial viability. It also fills in the role for saving financial and regulatory collapses that could potentially lead to risks; hence risk mitigation is an indirect role for these offices. Though the idea of relatively new but has found traction at an accelerating pace. The objective of this study is to find out common successful strategies from different technology transfer offices (TTOs)in three countries from i.e. USA, India and Kenya. Their choice reflects a case where extreme ends of the spectrum will be evaluated (USA and Kenya) and India in the middle with some infrastructure that remains in place while a lot of work remains pending. The paper critically identified the diverse strategies implemented by these TTOs, aiming to discern the variations in their approaches and uncover the elements that prove effective. The research covering above jurisdictions also have a focus on TTOs from academic Institutions. It is important to understand the public funded academic Institutions from selected jurisdictions, as the success strategies would be a key learning factor for TTOs from various other academic institutions.